Hyperthermia - symptom, Treatment of Hyperthermia
Hyperthermia is characterized by an unchanged (normothermic) setting of the thermoregulatory center in conjunction with an uncontrolled increase in body temperature that exceeds the body's ability to lose heat. Exogenous heat exposure and endogenous heat production are two mechanisms by which hyperthermia cap result in dangerously high internal temperatures.
Excessive heat production can easily cause hyperthermia despite physiologic and behavioral control of body temperature. For example, over-insulating clothing can result in an elevated core temperature, and work or exercise in hot environments can produce heat faster than peripheral mechanisms can lose it.
Symptoms of Hyperthermia
Although most patients with elevated body temperature have fever, there are a few circumstances in which elevated temperature represents not fever but hyperthermia. Heat stroke, caused by thermoregulatory failure in association with a warm environment, may be categorized as exertional"or nonexertional.
Exertional heat stroke typically occurs in younger individuals exercising at ambient temperatures and/or humidities that are higher than normal. Even in normal individuals, dehydration or the use of common medications (e.g., overthe- counter antihistamines with anticholinergic side effects) may help to precipitate exertional heat stroke. Nonexertional or classic heat stroke typically occurs in elderly individuals, particularly during heat waves. For example, in Chicago in July 1995, 465 deaths were certified as heat related. The elderly, the bedridden, persons taking anticholinergic or aritiparkinsonian drugs or diuretics, and individuals confined to poorly ventilated and non-air-conditioned environments are most susceptible.
Treatment of Hyperthermia
Drug-induced hyperthermia has become increasingly common as aresult of the increased use of prescription psychotropic drugs and illicit drugs. Drug-induced hyperthermia may be caused by monoamine oxidase inhibitors, tricyclic antidepressants, and amphetamines and by the illicit use of phencyclidine, lysergic acid diethylamide (LSD), or cocaine.
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