Kaposis Sarcoma - symptom, Treatment of Kaposis Sarcoma
Kaposis Sarcoma Information
Kaposi's sarcoma is a form of skin cancer that can involve internal organs. The etiology of KS remains unknown, but evidence suggests that the disease is promoted by the effects of immunosuppression and immune activation, possibly combined with a sexually transmissible infectious agent. This diseases is is more likely to afflict men than women suggests sex hormones, such as testosterone in men, may stimulate the growth of KS tumors, and that estrogen in women may retard their growth. There are four main types of KS They are all more common in men than women.
Symptoms of Kaposis Sarcoma
Kaposi's sarcoma produces pink, purple, or brown tumors on the skin, mucous membranes, or internal organs. KS can also affect other parts of the body, most commonly the lymph nodes, the lungs and the organs of the digestive system. KS most commonly involves the skin, although involvement of the lymph nodes, the oral cavity, and gastrointestinal tract are often seen at presentation.
Causes of Kaposis Sarcoma
A variety of factors appear to contribute to the development of KS. Most KS is now believed to be caused by a virus called Human Herpes Virus 8 (HHV8), which is also known as Kaposi's Sarcoma-associated Herpes Virus (KSHV). The virus can be passed on through sexual contact, kissing, blood transfusions and organ transplantation.
Treatment of Kaposis Sarcoma
If a diagnosis of KS is confirmed, further tests are usually done to see if there are any signs of KS cells elsewhere in your body. Therapeutic approaches must take into account that there is no curative therapy, that the natural course of the disease may be quite variable and that a large number of systemic approaches have immunosuppressive effects.
A trial is currently underway to evaluate low-dose oral etoposide for the treatment of relapsed or progressed KS after systemic chemotherapy.
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