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Home :: Endometrial Hyperplasia
Endometrial Hyperplasia - Symptom, Causes, Treatment of Endometrial Hyperplasia
Endometrial hyperplasia is an abnormal proliferation of the endometrium, in excess of the normal proliferation that occurs during the menstrual cycle. It is due to due to prolonged stimulation by the female sex hormone oestrogen, without the balancing effect of progesterone. Simple hyperplasia (without atypia) means the lining of the uterus is thick but the basic structure of the endometrium is relatively unchanged. It affects about one out of 1000 women in the United States. Endometrial hyperplasia is not usually a serious condition but. if it is not controlled, prolonged stimulation by oestrogen may lead to endometrial cancer. There are four types of endometrial hyperplasia:
- Simple
- Complex
- Simple atypical
- Complex atypical.
Symptoms of Endometrial Hyperplasia
Symptoms of this disorder includes - irregular vaginal bleeding, heavy or prolonged menstrual cycles, and post-menopausal bleeding in older women. It usually presents clinically as abnormal vaginal bleeding (intermenstrual, polymenorrhoea or postmenopausal), Vaginal discharge, Glandular abnormalities on a cervical smear.
Treatment of Endometrial Hyperplasia
Treatment options for this disease include:
- Cystic hyperplasia in a young woman may be treated with either cyclical progestogen or an oral contraceptive pill.
- Dilatation and curettage
- Endometrial ablation
- Hysterectomy.
- Simple endometrial hyperplasia without atypia responds to high dose oral progestogens, with repeat histology after three months. Hysterectomy is advised for atypical endometrial hyperplasia.
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